Taller 11. Enfermedades Hereditarias (cap 15) 1. Mutations are alterations in the nucleotide sequence of DNA. They may be changes in single nucleotides or extensive rearrangements of chromosomes. If they occur in somatic cells, they will be passed on to...
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Taller 11. Enfermedades Hereditarias (cap 15) 1. Mutations are alterations in the nucleotide sequence of DNA. They may be changes in single nucleotides or extensive rearrangements of chromosomes. If they occur in somatic cells, they will be passed on to daughter cells; if they occur in germ line cells, they will be passed on to offspring. a. What are the various kinds of point mutations? See pp. 318–320 and Figure 15.2 b. What distinguishes the various kinds of chromosomal mutations: deletions, duplications, inversions, and translocations? See p. 320 and Figure 15.4 c. Explain the difference between spontaneous and induced mutagenesis. Give an example of each. See pp. 320–322 and Figure 15.5 d. Why do many mutations involve G-C base pairs? See p. 322 and Figure 15.6. See pp. 895–896 and Figure 42.19 2. Large DNA molecules can be cut into smaller pieces by restriction digestion and then sorted by gel electrophoresis. PCR is used to amplify sequences of interest from complex samples. The
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