Thymosin ß4 a "moonlighting protein" 1
Thymosin ß4 (TB4) is a "moonlighting protein" 1 .
Simply put it is multi-functional.
While that may
seem to be a concept that is simple to grasp, after-all multi-functional simply means it does a bunch of
different...
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Thymosin ß4 a "moonlighting protein" 1
Thymosin ß4 (TB4) is a "moonlighting protein" 1 .
Simply put it is multi-functional.
While that may
seem to be a concept that is simple to grasp, after-all multi-functional simply means it does a bunch of
different things, in reality, in the context of biology to label a peptide a "moonlighting protein" adds
complexity to our understanding of when, how and to what extent that peptide act.
As an analogy, in
our world a fork residing in the hand of the hungry will function as a tool for getting food into mouth.
Remove that fork from the kitchen and put it in the hand of someone in a life threatening situation and
it becomes a weapon.
Whether that fork-weapon is used to inflict damage or defend against it depends
on the tissue that holds it.
In other words the multi-fuction of the fork never depends on the fork itself.
The function always depends on where it resides and the hand that holds it, be it a hungry hand, angry
hand or a scared hand.
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