Molmed TK ASH: Long term assessment presented at the 54th Annual Meeting

Milan (Italy), 10 December 2012 – MolMed S.p.A. (MLM.MI) announces the presentation of the long term clinical benefit and safety data of its investigational cell-based therapy TK at the 54th Annual Meeting of the American Society of Hematology (ASH) in... More

Milan (Italy), 10 December 2012 – MolMed S.p.A. (MLM.MI) announces the presentation of the long term clinical benefit and safety data of its investigational cell-based therapy TK at the 54th Annual Meeting of the American Society of Hematology (ASH) in Atlanta (GA, U.S.). The overall analysis comprises 128 patients with high-risk haematological malignancies who were treated in different countries in 10 Phase I-II clinical trials with TK cells, i.e. genetically engineered donor T cells administered after haematopoietic stem cell transplants from healthy donors to improve the graft-versus-leukaemia effect and to hasten patient immune reconstitution. Notably, no adverse events correlated to the use of TK cells were ever reported. Graft versus Host Disease (GvHD) was reported in 28 patients which, in all cases was rapidly and completely controlled thanks to the TK technology without the need of high-dose immunosupression following the transplant. These results confirm the feasibility, s Less