Cytogenetics correlates structural and numerical changes
in chromosomes with their clinical effects (phenotype).
Individual chromosomes can be distinguished using
various staining or banding techniques to create a unique
pattern of light- and darkstained...
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Cytogenetics correlates structural and numerical changes
in chromosomes with their clinical effects (phenotype).
Individual chromosomes can be distinguished using
various staining or banding techniques to create a unique
pattern of light- and darkstained regions (bands) along the
length of each chromosome.
This banding allows recognition of each chromosome pair
numbered 1-22 and the X and Y chromosomes, as well as
a detailed analysis of their structure.
High resolution
chromosome analysis implements special techniques to
extend the length and resolution of banding patterns,
allowing better detection of minute chromosomal
alterations that may be found, for example, in children
with developmental delay.
Cytogenetic Testing
(Chromosome Analysis/ Karyotyping)
Chromosome analysis can be helpful
for the patients with:
Prenatal
• Abnormal maternal sera results
• Advanced maternal age
• Ultrasound anomalies
• Parental balanced anomalies (ie translocations)
• Multiple spontaneous abortions
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