Report on Ethiology, epidemiology, pathogenesis, clinical features and the treatment principles of cholera. Dehydration – Rehydration. Report prepared by 1. Dr. Sajid Mahmood, MD (EU), Accident & Emergency Department, NHS Royal infirmary Liverpool United

-pg-1 Ethiology, epidemiology, pathogenesis, clinical features and the treatment principles of cholera. Dehydration – Rehydration. Cholera is a acute diarrheal disease involving the entire small bowel and that can cause death due to dehydration within... More

-pg-1 Ethiology, epidemiology, pathogenesis, clinical features and the treatment principles of cholera. Dehydration – Rehydration. Cholera is a acute diarrheal disease involving the entire small bowel and that can cause death due to dehydration within several hours. 1) Etiology: - Vibrio Cholerae: It is curved, motile, flagellated Gr Negative bacteria ( Aerobic Rod) - The organism is killed by 100°C temperature in few seconds but can survive in ice for up to 6 weeks. - 2 Main sero groups – O1 & O139 Bengal O1 has 2 biotypes – classical & El tor and 3 serotypes Inaba, Ogawa, Hikojima (All three strains are pathogenic) - Vibra Cholerae Vibrae Heamolyticus Non Invasive Invasive Affects Small Bowel Affects Colon (Proximal Mainly) - El Tor is the major cause of cholera now as it is a hardier organism. Infection with El Tor is frequently unrecognized because it produces milder clinical symptoms. 2) Epidemiology: - Hosts : Human - Cholera is spread by ingestion of H2O, seafood or other Less