NICE clinical guideline 101
Developed by the National Collaborating Centre for Acute and Chronic Conditions
Issue date: June 2010
Chronic obstructive
pulmonary disease
Management of chronic obstructive
pulmonary disease in adults in primary
and secondary care (partial update)
This guideline partially updates and
replaces NICE clinical...
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NICE clinical guideline 101 Developed by the National Collaborating Centre for Acute and Chronic Conditions Issue date: June 2010 Chronic obstructive pulmonary disease Management of chronic obstructive pulmonary disease in adults in primary and secondary care (partial update) This guideline partially updates and replaces NICE clinical guideline 12
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From perez.josea
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Pub. on March 3rd 2011
Pages: 61
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Evaluation & the Health Professions / March 2002
Chalmers et al.
/ A BRIEF HISTORY
Science is supposed to be cumulative, but scientists only rarely cumulate evidence scientifically.
This means that users of research evidence have to cope with a plethora of reports
of individual studies with no systematic
attempt made to present new...
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Evaluation & the Health Professions / March 2002 Chalmers et al. / A BRIEF HISTORY Science is supposed to be cumulative, but scientists only rarely cumulate evidence scientifically. This means that users of research evidence have to cope with a plethora of reports of individual studies with no systematic attempt made to present new results in the context of similar studies. Although the need to synthesize research evidence has been recognized for well over two centuries, explicit methods for this form of research were not developed until the 20th century. The development of methods to reduce statistical imprecision using quantitative synthesis (meta-analysis) preceded the development of methods to reduce biases, the latter only beginning to receive proper attention during the last quarter of the 20th century. In this article, the authors identify some of the trends and highlights in this history, to which researchers in the physical, natural, and social sciences have all contribut
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Pub. on Jan. 17th 2011
Pages: 26
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Diagnosis and Management of Stable Chronic Obstructive Pulmonary
Disease: A Clinical Practice Guideline from the American College
of Physicians
Amir Qaseem, MD, PhD, MHA; Vincenza Snow, MD; Paul Shekelle, MD, PhD; Katherine Sherif, MD; Timothy J.
Wilt, MD, MPH;
Steven Weinberger, MD; and Douglas K.
Owens, MD, MS, for the Clinical...
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Diagnosis and Management of Stable Chronic Obstructive Pulmonary Disease: A Clinical Practice Guideline from the American College of Physicians Amir Qaseem, MD, PhD, MHA; Vincenza Snow, MD; Paul Shekelle, MD, PhD; Katherine Sherif, MD; Timothy J. Wilt, MD, MPH; Steven Weinberger, MD; and Douglas K. Owens, MD, MS, for the Clinical Efficacy Assessment Subcommittee of the American College of Physicians* Recommendation 1: In patients with respiratory symptoms, particularly dyspnea, spirometry should be performed to diagnose airflow obstruction. Spirometry should not be used to screen for airflow obstruction in asymptomatic individuals. (Grade: strong recommendation, moderate-quality evidence. ) Recommendation 2: Treatment for stable chronic obstructive pulmonary disease (COPD) should be reserved for patients who have respiratory symptoms and FEV1 less than 60% predicted, as documented by spirometry. (Grade: strong recommendation, moderatequality evidence. ) Recommendation 3: Clinician
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From perez.josea
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Pub. on Apr. 15th 2010
Pages: 7
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Diciembre 2009 - Volumen I
Ficha
Publicación de la Dirección General de Farmacia y Productos Sanitarios
Evaluación de la bioequivalencia de una
formulación genérica de atorvastatina
comparada con la formulación de referencia nº 44
Índice de contenidos
Conclusiones
• La bioequivalencia y los estudios de bioequivalencia
•...
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Diciembre 2009 - Volumen I Ficha Publicación de la Dirección General de Farmacia y Productos Sanitarios Evaluación de la bioequivalencia de una formulación genérica de atorvastatina comparada con la formulación de referencia nº 44 Índice de contenidos Conclusiones • La bioequivalencia y los estudios de bioequivalencia • La atorvastatina, características farmacocinéticas • Estudio de bioequivalencia de atorvastatina farma ratio 40 mg comprimidos recubiertos EFG (farma ratio) vs lipitor® 40 mg comprimidos (Pfizer Ireland Pharmaceuticals) • Atorvastatina de referencia VS genérica: valoración del impacto sobre el ahorro • Conclusiones 1. Las dos formulaciones de atorvastatina fueron bien toleradas con un perfil de seguridad similar. 2. Las dos formulaciones de atorvastatina se considera que son intercambiables. 3. La prescripción de la formulación genérica supondría un ahorro de más de 20 millones de € en un periodo de 9 meses (periodo estudiado: enero – septiembre 2009).
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From perez.josea
This Provisional PDF corresponds to the article as it appeared upon acceptance.
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PDF and full text (HTML) versions will be made available soon.
Pharmacotherapy in pulmonary arterial hypertension: A systematic review and
meta-analysis
Respiratory Research 2010, 11:12 doi:10.
1186/1465-9921-11-12
Christopher J...
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This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon. Pharmacotherapy in pulmonary arterial hypertension: A systematic review and meta-analysis Respiratory Research 2010, 11:12 doi:10. 1186/1465-9921-11-12 Christopher J Ryerson (cryerson@interchange. ubc. ca) Shalini Nayar (nayar_shalini@hotmail. com) John R Swiston (swiston@interchange. ubc. ca) Don D Sin (dsin@mrl. ubc. ca) ISSN 1465-9921 Article type Research Submission date 13 November 2009 Acceptance date 29 January 2010 Publication date 29 January 2010 Article URL http://respiratory-research. com/content/11/1/12 This peer-reviewed article was published immediately upon acceptance. It can be downloaded, printed and distributed freely for any purposes (see copyright notice below). Articles in Respiratory Research are listed in PubMed and archived at PubMed Central. For information about publi
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From perez.josea
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Pub. on Feb. 3rd 2010
Pages: 35
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Técnicas de Urgencias
Libro electrónico de Temas de Urgencia
1
VENTILACIÓN NO INVASIVA EN INSUFICIENCIA RESPIRATORIA AGUDA (IRA)
José Ignacio Elejalde (M Interna HVC) y Juan Pedro Tirapu (UCI HN)
1.
CONSIDERACIONES INICIALES:
1.
1.
La ventilación no invasiva es un tipo de soporte ventilatorio artificial mecánico o no
mecánico...
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Técnicas de Urgencias Libro electrónico de Temas de Urgencia 1 VENTILACIÓN NO INVASIVA EN INSUFICIENCIA RESPIRATORIA AGUDA (IRA) José Ignacio Elejalde (M Interna HVC) y Juan Pedro Tirapu (UCI HN) 1. CONSIDERACIONES INICIALES: 1. 1. La ventilación no invasiva es un tipo de soporte ventilatorio artificial mecánico o no mecánico que facilita la mecánica ventilatoria. Modifica el patrón ventilatorio de la insuficiencia respiratoria aguda (respiración rápida y superficial), reduciendo la frecuencia respiratoria y aumentando el volumen corriente y favoreciendo la ventilación alveolar (reduce le colapso alveolar mejorando el reclutamiento alveolar y por lo tanto el shunt) con una presión positiva que se aplica a través de mascarillas nasales, nasobucales o faciales, sin necesidad de intubación endotraqueal y supone una alternativa a la ventilación mecánica invasiva en algunas indicaciones clínicas. Existen en la actualidad opciones de ventilación no invasiva con presión negativa a través
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From perez.josea
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Pub. on Jan. 18th 2010
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This Provisional PDF corresponds to the article as it appeared upon acceptance.
Fully formatted
PDF and full text (HTML) versions will be made available soon.
Individual-level socioeconomic status is associated with worse asthma
morbidity in patients with asthma
Respiratory Research 2009, 10:125 doi:10.
1186/1465-9921-10-125
Simon L...
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This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon. Individual-level socioeconomic status is associated with worse asthma morbidity in patients with asthma Respiratory Research 2009, 10:125 doi:10. 1186/1465-9921-10-125 Simon L Bacon (simon. bacon@concordia. ca) Anne Bouchard (tigrann@hotmail. com) Eric B Loucks (eric. loucks@brown. edu) Kim L Lavoie (kiml_lavoie@yahoo. ca) ISSN 1465-9921 Article type Research Submission date 5 July 2009 Acceptance date 17 December 2009 Publication date 17 December 2009 Article URL http://respiratory-research. com/content/10/1/125 This peer-reviewed article was published immediately upon acceptance. It can be downloaded, printed and distributed freely for any purposes (see copyright notice below). Articles in Respiratory Research are listed in PubMed and archived at PubMed Central. For information about publishing your research in Respiratory
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From perez.josea
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Pub. on Dec. 25th 2009
Pages: 23
Views: 16
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DOI 10.
1378/chest.
129.
1.
88
2006;129;88-94Chest
Berndt Lüderitz and Selçuk Tasci
Silvia Lentini, Robert Manka, Sabine Scholtyssek, Birgit Stoffel-Wagner,
Unknown Association?
Obstructive Sleep Apnea Syndrome: An
Creatine Phosphokinase Elevation in
http://chestjournals.
org/cgi/content/abstract/129/1/88
and services...
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DOI 10. 1378/chest. 129. 1. 88 2006;129;88-94Chest Berndt Lüderitz and Selçuk Tasci Silvia Lentini, Robert Manka, Sabine Scholtyssek, Birgit Stoffel-Wagner, Unknown Association? Obstructive Sleep Apnea Syndrome: An Creatine Phosphokinase Elevation in http://chestjournals. org/cgi/content/abstract/129/1/88 and services can be found online on the World Wide Web at: The online version of this article, along with updated information ). ISSN: 0012-3692. http://www. chestjournal. org/misc/reprints. shtml( of the copyright holder may be reproduced or distributed without the prior written permission Northbrook IL 60062. All rights reserved. No part of this article or PDF by the American College of Chest Physicians, 3300 Dundee Road, 2007Physicians. It has been published monthly since 1935. Copyright CHEST is the official journal of the American College of Chest Copyright © 2006 by American College of Chest Physicians on April 11, 2007chestjournals. orgDown
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Pub. on Dec. 14th 2009
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