HIV Cure Research Workshop Clinical Report

PRESS RELEASE HIV CURE RESEARCH WORKSHOP CLINICAL REPORT Following the last "International Workshop on HIV Persistence, Reservoirs and Eradication Strategies", scientists are now working into translating the recent basic discoveries into clinical trials for... More

PRESS RELEASE HIV CURE RESEARCH WORKSHOP CLINICAL REPORT Following the last "International Workshop on HIV Persistence, Reservoirs and Eradication Strategies", scientists are now working into translating the recent basic discoveries into clinical trials for patients. Toulon, France, January 04, 2012 -- Although a number of promising approaches have led to testable hypotheses for an HIV cure, for which small animal and primate models may provide preliminary information, ultimately proof of concept and validation studies in human subjects will be required. These trials will need to balance the risks of significant toxicity, morbidity and mortality of novel strategies against the possible benefit to individual patients and knowledge gained overall. However, it is challenging to define an acceptable level of risk in the context of generally safe and effective life-long therapy. Would a small risk of fatal complication be acceptable? Would a modest risk of mortality, like 1-2% for coron Less