An Update on Tourette Syndrome
Thomas E.
Kimber
Published online: 6 May 2010
# Springer Science+Business Media, LLC 2010
Abstract Recent advances in our understanding of the
phenomenology, etiology, pathophysiology, and treatment
of Tourette syndrome are...
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An Update on Tourette Syndrome
Thomas E.
Kimber
Published online: 6 May 2010
# Springer Science+Business Media, LLC 2010
Abstract Recent advances in our understanding of the
phenomenology, etiology, pathophysiology, and treatment
of Tourette syndrome are discussed.
Tourette syndrome
appears to involve dysfunction of limbic and somatosensory “traffic” through the basal ganglia, within corticostriatalthalamocortical circuits.
Dynamic alterations in the balance
of these inputs may dictate the manifestations (sensory,
motor, affective, and behavioral) of the disorder at any
given time.
Individualized assessment and treatment are the
keys to optimal treatment of this condition.
Keywords Movement disorders .
Tourette .
Deep brain
stimulation .
Neuropsychiatric .
Tics
Introduction
Tourette syndrome (TS) is a disorder characterized by the
occurrence of multiple motor and phonic tics and, in most
cases, by psychiatric features such as obsessive-compulsive
disorder (OCD), attention defi
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